The authors document the cytological features on fine-needle aspiration cytology of a chondroblastoma which appeared as a lytic lesion in the. Chondroblastoma is an uncommon benign cartilage producing neoplasm with a characteristic epiphyseal location. This report documents the. Chondroblastoma is a rare primary bone tumor of young people .. Fine needle aspiration cytology of chondroblastoma of bone. Cancer.

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Metastases are unusual but occur in the lungs at chondroblqstoma time of recurrence. J Bone Joint Surg Am ; There was no recurrence observed on 2-year follow-up of the case.

Fine needle aspiration cytology of chondroblastoma of the fibula

The intramedullary cartilage tumors. Smears characteristically revealed chondroblasts and osteoclast-like giant cells. Magnetic resonance imaging knee joint short tau inversion recovery Coronal reveals abnormal hyperintense medullary marrow signal in the head of fibula epiphysis extending inferiorly into upper shaft of the fibula.

Correlating the above cytomorphology with chonsroblastoma clinical and radiological details, cytological diagnosis of CMF was offered in both the cases.

In correlation with the radiological findings, a provisional diagnosis suggestive of chondroblastoma was offered.

Pathology Outlines – Chondroblastoma

In the second case, due to the location of the tumor in preauricular region, cartilaginous stroma aspirated was misinterpreted as chondroid stroma of pleomorphic adenoma in the salivary gland. Fine needle aspiration cytology in the management of tumors and tumor like lesions of bone. The chondromyxoid matrix appeared as dense fibrillary irregular cytolgoy, which was best appreciated in MGG-stained smears due to its magenta-pink to purple color [Figure – 2].


Although fine needle aspiration cytology FNAC is gaining acceptance as very convenient and reliable method for the rapid diagnosis of bone lesions, very few cases of chondroblastoma diagnosed on cytology have been reported in the literature. Armed Forces Institute of Pathology; Report of a case and review of literature.

At surgery, curettage and bone grafting was performed. Fine needle aspiration cytology. Abstract Chondroblastoma is a rare benign cartilaginous tumor typically seen in long bones, especially femur, tibia and proximal humerus. Chondroblaatoma of the cells were round to oval with well-defined borders, moderate cytoplasm and centric to eccentric round to ovoid nucleus. Benign cartilaginous tumors almost always appear benign on radiology with sharp circumscribed borders, intact overlying periosteum and no adjacent soft tissue swelling.

Smears were highly cellular, polyhedral cells arranged in sheets and small clusters, giving a pebble stone pattern appearance. Report of a case. Extremely well circumscribed tumor of epiphysis with spotty calcifications in patient with open epiphysis. The cytologic diagnosis of chondroblastoma was confirmed on both cases by histopathology.

Histopathology in both the cases showed sheets of polygonal cells with thick cell membranes and fine pale cytopogy cytoplasm. National Center for Biotechnology InformationU. A case report and review of literature.

FNAC was followed by curettage. Case 2 A year-old male presented with diffuse swelling on the shoulder joint of 1-month duration. FNA is fast gaining acceptance as an accurate and rapid technique for diagnosing osseous neoplasms. A Reinterpretation of the so-called calcifying or chondromatous giant cell tumor.

Chondromyxoid fibroma of the mandible: Their cytoplasm was dense with rounded well-defined borders. Arch Pathol Lab Med ; It usually affects the young with a peak incidence in the second and third decades of life and a slight male preponderance.


Conflicts of interest There are no conflicts of interest. A brief review of literature is also undertaken. Benign chondroblastoma of bone. Recognition of chondroblasts based on its cytological features has been emphasized as the diagnostic hallmark of this lesion along with chondroid matrix surrounding the individual cells. In both the cases, sections studied showed pseudo-lobules of myxoid and chondroid tissue separated by zones of fibrous tissue [Figure – 3].

Published online May The sites of predilection are long tubular bones in about half the cases, particularly distal femur and proximal tibia, while in one third of cases flat bones, such as the ileum, are involved. How to cite this article: A useful immunohistochemical marker for diagnosing chondroblastoma. This report reiterates the cytomorphologic findings in chondroblastoma and its differential diagnosis from other giant cell containing lesions of bone.

Cytological diagnosis of chondroblastoma: diagnostic challenge for the cytopathologist

Thus CMF was confirmed on histopathology. Journal List J Cytol v. This, compounded with nonconforming radiological features, leads to the tragic delay in diagnosis.

Presence of chondroid matrix is believed to be the decisive feature to differentiate chondroblastoma from giant cell tumor, which is seen better in Giemsa-stained smears than in Papanicolaou-stained smears.

Fine needle aspiration cytology of chondroblastoma cnondroblastoma bone. An year-old-female presented with pain in left leg for last 1-month and progressively increasing swelling around the knee joint for last 15 days.